Top Biotech Companies in Philadelphia 2023 – Expert Guide

1.Integral Molecular

Integral Molecular is a research-driven biotechnology company creating innovative technologies and therapeutic antibodies for under-exploited membrane protein targets, including GPCRs, ion channels, transporters, and viral envelopes.

At Integral Molecular, our greatest strength is our diverse scientific team. Our scientists have extensive expertise in membrane proteins, antibodies, structural biology, and virology, which we apply to provide exceptional solutions and tackle challenging therapeutic targets.Integral Molecular’s leadership team has been working together for 20 years, creating innovative products and technologies to address complex scientific questions.


MPS Antibody Discovery


Epitope Mapping

Membrane Proteome Array

Vaccine Development

Contact no: +1 215-966-6061

Address:3711 Market St #900, Philadelphia, PA 19104, United States


2.Bioquark Inc

Bioquark, Inc. is a life sciences company developing proprietary combinatorial biologic products for both the regeneration and repair of human organs and tissues, as well as the reversion of a range of chronic degenerative diseases.

Bioquantine Programs


BQ-A In-Vivo Studies

BQ-A Clinical Plans

Health, Wellness and Beauty Care

Articles / Shows / Press Releases / Publications

Future Bioquantine Programs

Contact no: +1 267-507-6155

Address:1735 Market St #3750, Philadelphia, PA 19103, United States


3.Spark Therapeutics

About Gene Therapy

The goal of gene therapy is to treat or possibly prevent disease. Scientists have been investigating and evolving gene therapy for more than 50 years. One goal of gene therapy research is to determine whether a new or functional gene can be used to restore the function of, or inactivate, a mutated gene.

At Spark Therapeutics, we are using adeno-associated viral (AAV) vectors to advance research programs against strategically selected cell targets, for example, the retina, liver and central nervous system.

Contact no: +1 888-772-7560

Address: 3737 Market St, Philadelphia, PA 19104, United States



Novapeutics LLC is a biopharmaceutical company spun-out from the University of Pennsylvania that aims to develop a first-in-class, oral curative therapeutic to reverse the course of diabetes by regenerating insulin-producing beta cells. Our approach utilizes small molecule therapeutics to to disrupt menin and mixed lineage leukemia (MLL) proteins, known as a menin inhibitor, which enhances endogenous beta cell regeneration in diabetes patients. Currently with the support of the SBIR funding from NIH/NIDDK, we have identified promising novel menin inhibitors as our drug leads.

Address:3401 Grays Ferry Ave #213, Philadelphia, PA 19146, United States


5.Longevity Biotech, Inc

Longevity Biotech is developing a new class of therapeutic candidates called Hybridtides®. Our focus is on delivering clinically transformative products that tackle the most challenging aspects of medicine today. The unique Hybridtide® scaffold provides critical enhancements over previous peptide development efforts. Contact us to learn more.


Neuroscience – LBT-3627

Diabetes – LBT-6030

Contact no:+1 215-689-1042

Address:600 S 43rd St, Philadelphia, PA 19104, United States



Biomeme designs and manufactures precision portable instrumentation and test kits for DNA analysis and microbial detection in the field. We are a small but fast-growing company in this emerging tech space. Our products are being deployed in a variety of field settings throughout the world. However, much of our production today is focused on diagnostics to combat the SARS-Cov-2 Pandemic at the point of use. To do so, we need help and need it quick. Please take a look at the opportunities listed below and reach out now.


DNA & RNA Purification

Real-Time PCR Tests

Mobile qPCR Thermocyclers

PCR Mobile Apps

PCR Data Management Services

Biomeme Web API

Contact no:: +1 267-930-7707

Address:1015 Chestnut St #1401, Philadelphia, PA 19107, United States



Oscar Perez-Leal, MD and Matt Handel established ExpressCells in 2018 with the mission to improve drug development and basic biological research by creating better cell lines. We do so using genetic engineering technology invented by Dr. Perez at the Temple University School of Pharmacy. Our primary focus is on creating research tools that will speed drug discovery and provide better disease models for basic researchers. The company is a proud member of the growing Philadelphia life sciences community and our labs are located at Biolabs at CIC in University City, Philadelphia.

Our Technology

Gene Tagging

Overexpression Models

Contact no:+1 484-483-6759

Address:3675 Market St #200, Philadelphia, PA 19104, United States


8.Frontida BioPharm, Inc.

Frontida BioPharm, Inc. is a US-based, minority-owned CDMO providing drug delivery technologies, product development, and manufacturing services for pharmaceutical and consumer health companies. Our experts are dedicated to helping clients and partners reach the market as quickly and efficiently as possible. Frontida supports pharmaceutical companies in the development, scale-up and commercial manufacturing of immediate and controlled-release oral solid dose, powder and liquid products; ensuring robust product performance and on-time supply of clinical trial materials and commercial products.

Contact no: +1 215-288-6500

Address:1100 Orthodox St, Philadelphia, PA 19124, United States


9.Aro Biotherapeutics

A common challenge across RNA and DNA based therapeutics is the inability to selectively target gene modulating therapies to diseased tissues. This lack of efficient, targeted delivery can lead to insufficient activity of the drug in tissues of interest and excessive toxicity in non-diseased tissues.

Our Science

Partnerships & Collaborations


Contact Us


Centyrin Platform

Oligonucleotide-Based Therapeutics

Oligonucleotide Conjugates

Our Pipeline

Scientific Publications

Address:3675 Market St, Philadelphia, PA 19104, United States


10.Bio-Rad Laboratories, Inc., Informatics Division

Bio-Rad is a global leader in developing, manufacturing, and marketing a broad range of innovative products for the life science research and clinical diagnostic markets. With a focus on quality and customer service for over 65 years, our products advance the discovery process and improve healthcare. Our customers include university and research institutions, hospitals, public health and commercial laboratories, biotechnology, pharmaceutical, as well as applied laboratories that include food safety and environmental quality.

Our Products

Life Science Research


Clinical Diagnostics

Process Separations

Food Science

Life Science Education

Contact no:+1 267-322-6931

Address:2000 Market St #1460, Philadelphia, PA 19103, United States


Tajinder Singh: