1.Vertex Pharmaceuticals
Vertex creates new possibilities in medicine to cure diseases and improve people’s lives. We work with leading researchers, doctors, public health experts and other collaborators who share our vision for transforming the lives of people with serious diseases, their families and society.
Understanding CF
Lungs IconLungs Icon
Vertex’s Cystic Fibrosis Journey
Patient Advocacy
Vertex CF Community and Grant Programs
The Vertex and CookTracks Podcast Series
Contact no:+1 617-341-6100
Address: Drydock Ave, Boston, MA 02210, United States
Website:https://www.vrtx.com/
2.Alexion Pharmaceuticals Inc.
People living with rare and devastating diseases are our Guiding Star. We believe it is our responsibility to listen to, understand, and change the lives of patients and those who work tirelessly to help them.
We continue to deepen our understanding of rare disease, which began with our pioneering work in complement biology. This knowledge allows us to innovate and evolve into new areas, where there is great unmet need and opportunity to help patients and families fully live their best lives.
We’ve delivered transformative medicines for people with paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), anti-aquaporin-4 (AQP4) antibody-positive neuromyelitis optica spectrum disorder (NMOSD), generalized Myasthenia Gravis (gMG), hypophosphatasia (HPP), and lysosomal acid lipase deficiency (LAL-D).
Medicine
Conditions We Treat
aHUS
FXa Bleeds
gMG
HPP
LAL-D
NMOSD
PNH
Contact no:+1 475-230-2596
Address:121 Seaport Blvd, Boston, MA 02210, United States
Website:https://alexion.com/
3.Paratek Pharmaceuticals Inc
Positive outcomes. Positive patient stories. These are our priorities at Paratek Pharmaceuticals. We develop transformative solutions for patients with infectious diseases and other difficult to treat conditions, and we believe that with the right people, the right knowledge and the right drug, we can make a difference in patients’ lives.
To create positive stories for patients, physicians and caregivers based on trust and integrity. To accomplish this, our employees work hard to turn every day decisions into everyday triumphs that advance our technology and strengthen Paratek.
Contact no:: +1 617-807-6600
Address:75 Park Plaza 4th floor, Boston, MA 02116, United States
Website:https://www.paratekpharma.com/
4.Keryx Biopharmaceuticals, Inc.
Since our founding in 2007, we’ve put tenacity and innovation to work to develop unique therapeutics that have the potential to set new standards of care for people living with kidney disease. We have emerged as a leader with deep roots in the renal community. Today, we are a fully integrated biopharmaceutical company with both an experienced nephrology-focused commercial team and a robust development organization.
We have a commercial product approved and marketed in the United States and a late-stage product candidate. Our lead product candidate, vadadustat, is an investigational oral hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), which completed global Phase 3 program for the treatment of anemia due to chronic kidney disease.
As part of our mission, we’re working to address complications of kidney disease and we currently market AURYXIA® (ferric citrate) in the U.S. for its two approved indications:
Important Safety Information
CONTRAINDICATION
AURYXIA® (ferric citrate) is contraindicated in patients with iron overload syndromes, e.g., hemochromatosis
WARNINGS AND PRECAUTIONS
Iron Overload: Increases in serum ferritin and transferrin saturation (TSAT) were observed in clinical trials with AURYXIA in patients with chronic kidney disease (CKD) on dialysis treated for hyperphosphatemia, which may lead to excessive elevations in iron stores. Assess iron parameters prior to initiating AURYXIA and monitor while on therapy. Patients receiving concomitant intravenous (IV) iron may require a reduction in dose or discontinuation of IV iron therapy
Risk of Overdosage in Children Due to Accidental Ingestion: Accidental ingestion and resulting overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years of age. Advise patients of the risks to children and to keep AURYXIA out of the reach of children
Contact no: +1 617-466-3500
Address:1 Marina Park Drive, Boston, MA 02210, United States
Website:https://akebia.com/
5.Acetylon Pharmaceuticals Inc
We are a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases.
At Bristol Myers Squibb, we work every day to transform patients’ lives through science. We combine the agility of a biotech with the reach and resources of an established pharmaceutical company to create a global leading biopharma company powered by talented individuals who drive scientific innovation.
We have the brightest people in the industry and believe that their diverse experiences and perspectives help to bring out our best ideas, drive innovation and achieve transformative business results.
Each day, our employees around the world work together for patients – patients are at the center of everything we do. They inspire us. They are the reason we come to work each day.
We are proud of the advancements we have made in oncology, hematology, immunology and cardiovascular disease, and we are dedicated to helping patients prevail over serious diseases through our diverse and promising pipeline and new scientific platforms. We are pursuing therapies at the forefront of scientific discovery with the goal of bringing an exciting new generation of life-changing treatments to patients. We aspire to be at the center of a vibrant healthcare innovation ecosystem, where academic research centers, biotech and biopharma companies all contribute to continued scientific advancement.
Contact no:1 617-245-1300
Address:70 Fargo St, Boston, MA 02210, United States
Website:https://www.bms.com/
6.SelectX Pharmaceuticals, Inc.
SelectX is an emerging biopharmaceutical company focused on the discovery and development of aminoglycoside therapeutics for unmet medical needs. SelectX has built the industry’s most advanced aminoglycoside drug and othes drugs for example: ED treatment online discovery platform and is leveraging it to develop novel best-in-class and first-in-class compounds for anti infective and other therapeutic applications.
The company’s most advanced program, development candidate SXP2523, is a next generation aminoglycoside antibiotic for drug resistant gram-negative hospital-acquired infections (HAIs). SXP2523 possesses broad spectrum coverage with excellent potency against Pseudomonas, Klebsiella, Acinetobacter, E. coli, and Staphylococcus.
SelectX is also developing a next generation inhaled aminoglycoside antibiotic for drug resistant gram-negative infections in patients with Cystic Fibrosis (CF) and other respiratory diseases.
In addition to its antimicrobial programs, SelectX has efforts underway to identify and optimize non-antibiotic aminoglycoside (naAG) leads for discovery programs targeting key pathways including cell migration, calcium channels, metalloproteinases, nonsense mutation correction, and antivirals .
Contact no:: +1 508-798-0216
Address:800 Boylston St, Boston, MA 02199, United States
Website:http://www.selectxpharm.com/
7.Merck Research Laboratories
We aspire to be the premier research-intensive biopharmaceutical company in the world
For 130 years, Merck (known as MSD outside of the U.S. and Canada) has been inventing life, bringing forward medicines and vaccines for many of the world’s most challenging diseases in pursuit of our mission to save and improve lives.
We demonstrate our commitment to patients and population health by increasing access to health care through far-reaching policies, programs and partnerships.
Today, we continue to be at the forefront of research to prevent and treat diseases that threaten people and animals – including cancer, infectious diseases, such as HIV and Ebola, and emerging animal diseases.
Research & products
Patients
Patients overview
Patient support programs
Patient resources
Patient & treatment education
Contact no: +1 617-992-2000
Address: 33 Avenue Louis Pasteur, Boston, MA 02115, United States
Website:https://www.merck.com/
8.Symbiosis Pharmaceutical Services
We created our purpose-built facility in Stirling, Scotland, specifically designed with biologic and small molecule production capabilities in mind to support biotech and speciality pharmaceutical companies worldwide that require small-scale injectable products.
Differing from most CMOs, from the day our operations commenced we offered rapid access to manufacturing slots and quick release of drug products to ensure tight timelines are successfully met. Naturally, this has been a real hit with our clients.
Our core manufacturing capability takes place within an MHRA-licensed facility, which enables our team to fill bulk volumes under 100 litres, including products that require aseptic liquid filling and lyophilisation, such as:
Biologics including mAb’s, proteins, peptides and RNA
Cytotoxic, cytostatic and high potent APIs including ADCs
Small molecules
Contact no: +44 1786 220000
Address: 625 Massachusetts Ave 2nd Floor, Cambridge, MA 02139, United States
Website:http://www.symbiosis-pharma.com/us/
9.Atea Pharmaceuticals, Inc.
Discovering and rapidly advancing potentially transformative antiviral therapies.
Atea is a clinical stage biopharmaceutical company focused on discovering, developing and commercializing therapies to address the unmet medical needs of patients with life-threatening viral diseases.
Leveraging the power of our medicinal chemistry expertise and purine nucleotide prodrug platform, we are focused on discovering, optimizing, and rapidly advancing novel drug candidates for viral targets such as SARS CoV-2.
RNA VIRUSES
The prevalent cause of severe human viral diseases.
Single-stranded positive-sense RNA viruses account for a large number of clinically serious global pathogens and are the cause of many potentially life-threatening diseases: coronaviruses, including SARS-CoV-2, the virus responsible for COVID-19, dengue, yellow fever, Ebola, Zika, West Nile, encephalitis viruses, hepatitis C, and RSV.
The activity of a key viral enzyme, RNA-dependent RNA polymerase, also known as RNA polymerase, is required for replication and propagation of these viruses. The structure of this enzyme is highly conserved across RNA viruses. Most viral RNA polymerases have been identified on the basis of comparative sequence analysis, but it is important to know that viral genome replication is initiated by two different and distinct mechanisms.
Contact no:+1 857-284-8891
Address:125 Summer St, Boston, MA 02110, United States
Website:https://ateapharma.com/
10.Novartis Pharmaceuticals
Our strategy is to build a leading, focused medicines company powered by advanced therapy platforms and data science.
Chief Talent and People Solutions Officer Tripti Jha’s mother prioritized her learning in a rural region of India with limited opportunities for girls.
Our purpose is to reimagine medicine to improve and extend people’s lives. We use innovative science and technology to address some of society’s most challenging healthcare issues. We discover and develop breakthrough treatments and find new ways to deliver them to as many people as possible. We also aim to reward those who invest their money, time and ideas in our company.
Navigate Novartis
Patients & Caregivers
Healthcare Professionals
Investors
Media
Society & ESG
Contact no: +1 617-577-0285
Address: 181 Massachusetts Ave, Cambridge, MA 02139, United States
Website:https://www.novartis.com/