What Level of Eosinophils Indicate Cancer. A high level of eosinophils alone is not an indication of cancer. However, it can be a sign of certain types of cancer such as Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and some types of gastrointestinal cancers. The diagnosis of cancer cannot be made solely on the basis of eosinophil count. Eosinophils are a kind of white blood cell that helps to fight disease. The role of eosinophils in the human body is concerned with allergic diseases and certain types of infection. The eosinophil cells are prepared in bone marrow from which they travel to other body parts and tissues. To have guidance and consultation regarding any treatment plan and diagnosis, you can consider approaching Hospital.
What Does a High Eosinophil Count Mean?
Eosinophils perform two important activities in the immune system. One is to curb infections and the other one is to boost inflammation. These two important factors help to fight infections. There is another term called eosinophilia that is related to eosinophils. This happens when a human body has a higher number of eosinophils cells in blood or tissue. This can be detected in blood tests. If this high range of numbers appears in the blood test, this is called an absolute eosinophil count. There are other types of tests to diagnose the type of medical condition associated with higher eosinophil count.
An eosinophil count helps detect a few conditions. If you have a higher count of eosinophil then you may be at risk of the following disease:
- Acute hypereosinophilic syndrome, similar to leukemia- a type of cancer and can be life-threatening
- asthma or hay fever
- Autoimmune conditions
- Vulnerable to infections that are caused by fungus and parasites
- Early stages of Cushing’s disease, a rare condition that is caused by the release of too much hormone called cortisol in your blood
- Eczema (itchy, inflamed skin)
- Leukemia (a cancer of blood and bone marrow) and other blood disorders
What Does a Low Eosinophil Count Mean?
Having an eosinophil count lower than normal could be a sign of the following conditions:
- If you have taken too much alcohol
- If your body is making too many steroids
The eosinophil test is used to measure the count or amount of eosinophil cells in the blood. The key to having an eosinophil test is to do the job and go away with the flow of life. But, if you have more than the normal count of eosinophil in your body for a long time, you may have a condition called eosinophilia. This condition can lead to inflammation in the body that can damage the tissues.
Eosinophilic disorders affect the different organs of the body. These include the stomach, blood, small intestine, or other organs. Sometimes, a biopsy is done to diagnose the high amount of eosinophils. Getting diagnosed for the test doesn’t necessarily mean that the body is incorporated with higher amounts of eosinophil cells in the blood.
level of eosinophils that indicates cancer or leukemia
Eosinophils are involved in the process that responds to infections, particularly those caused by parasites. Eosinophil cells also play an important role in allergic reactions. Eosinophils make up at least 5 percent of all white blood cells. Eosinophilic leukemia is the cancer of the blood that is indicated by the presence of a high number of eosinophils in the blood, bone marrow, and other tissues. When eosinophil count is higher than normal, it is called eosinophilia.
A normal level of eosinophils that should be present in the blood of a healthy human counts as 350 to 500 cells per cubic millimeter. A person has eosinophilia when the blood count of eosinophil is above 500 per cubic millimeter. In addition to the general effects of leukemia, having high counts of eosinophils in the blood can be damaging to human health. This is because eosinophils release chemicals that further harm organs and tissues.
What if you have a higher or lower level of eosinophils count in your body?
Eosinophils make up to 0 to 6% of human blood. The absolute count comes when this count of eosinophils is multiplied by the count of white blood cells. Each count of each different personality ranges a bit different. But, the usual range of eosinophils count is between 30 and 350. If the count of eosinophil cells is more than 500 cells per microliter of blood then the condition is considered as eosinophilia. Eosinophilia can be the sign of the presence of a variety of disorders or diseases in the human blood.
The eosinophil count helps to confirm the type of disease and the diagnosis. Once it is rectified that what has caused the eosinophilia, the patients are provided with the next step of treatment. You can also have other types of tests to get a diagnosis of a particular medical condition.
How is eosinophilic leukemia or blood cancer treated?
Generally, there is no standard treatment plan for eosinophilic leukemia. However, the treatment plan is suggested based on the different factors including the severity of the condition, age of the patient, and patient’s overall health.
Moreover, some potential treatment options include:
- Targeted therapy: The therapy targets some specific proteins or the cancer cells in the body. This therapy helps to kill and slow down the growth of cancerous cells. Imatinib is a drug that is used for targeted therapy and can treat eosinophilic leukemia.
- Chemotherapy: This therapy is used to kill cancer cells. This therapy utilizes the drugs that help to slow down the growth of cancer cells. The drugs like hydroxyurea (Hydrea) and cyclophosphamide (Cytoxan) can be used to treat eosinophilic leukemia.
- Interferon-alpha: It is a drug that is similar to interferon proteins. Interferon Proteins are naturally produced proteins made by the immune system of the human body. These proteins help to slow down the growth of leukemia cells.
- Corticosteroids: These are the special kind of drugs that help to reduce the activity of the immune system. With this, they interfere with the normal activity of eosinophil cells. The drugs are purposely used for the treatment of eosinophilic leukemia.
- Stem cell transplant: In this treatment plan, a high dose of chemotherapy is used to kill the cells developing at a faster pace in the bone marrow. This treatment affects both cancerous and healthy cells. After this, the patient’s body is infused with the stem cells from a healthy body to let the blood cells grow.
Where to seek help?
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Faq on What Level of Eosinophils Indicate Cancer
Q: What are eosinophils?
A: Eosinophils are a type of white blood cells that play a role in the immune system’s response to parasitic infections and allergic reactions. They are present in the blood and tissues of the body.
Q: Can a high level of eosinophils indicate cancer?
A: A high level of eosinophils alone is not an indication of cancer. However, it can be a sign of certain types of cancer such as Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and some types of gastrointestinal cancers.
Q: What is the normal range of eosinophils in the blood?
A: The normal range of eosinophils in the blood is usually between 0-450 cells per microliter (mcL). However, the range may vary depending on the laboratory and the testing method used.
Q: How is the level of eosinophils measured?
A: The level of eosinophils is measured through a blood test called a complete blood count (CBC).
Q: What is the significance of a high eosinophil count in cancer diagnosis?
A: A high eosinophil count in the blood, in combination with other clinical and laboratory findings, may raise the suspicion of cancer. However, the diagnosis of cancer cannot be made solely on the basis of eosinophil count.
Q: What other factors can cause a high eosinophil count?
A: A high eosinophil count can be caused by various factors such as allergies, asthma, parasitic infections, autoimmune diseases, and certain medications.
Q: How is cancer diagnosed if eosinophil count is high?
A: If a high eosinophil count is detected, additional tests such as imaging studies, biopsy, and other blood tests may be performed to diagnose cancer.
Q: What is the treatment for cancer associated with high eosinophil count?
A: The treatment for cancer associated with high eosinophil count depends on the type and stage of cancer. It may include surgery, chemotherapy, radiation therapy, or a combination of these therapies.
Q: Can a low eosinophil count indicate cancer?
A: A low eosinophil count is not typically associated with cancer, but it can be a sign of other health conditions such as bacterial infections, viral infections, and drug reactions.
Q: Should I be concerned if my eosinophil count is high?
A: If your eosinophil count is high, it is important to follow up with your healthcare provider to determine the underlying cause and to receive appropriate treatment if necessary. However, a high eosinophil count alone does not necessarily indicate cancer.